The impact of HIV on morbidity and mortality from tuberculosis in sub-Saharan Africa: a study of rural Malawi and review of the literature

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dc.contributor.authorGlynn, J. Ren_US
dc.contributor.authorWarndorff, D. Ken_US
dc.contributor.authorFine, P. E. Men_US
dc.contributor.authorMsiska, G. Ken_US
dc.contributor.authorMunthali, M. Men_US
dc.contributor.authorPonnighaus, J. Men_US
dc.contributor.editorAwusabo-Asare, Kofien_US
dc.contributor.editorPisani, Elisabethen_US
dc.contributor.editorBoerma, J. Tiesen_US
dc.contributor.editorZaba, Basiaen_US
dc.date.accessioned2003-03-12en_US
dc.date.accessioned2004-05-19T15:25:41Zen_US
dc.date.accessioned2011-01-05T08:36:14Z
dc.date.available2004-05-19T15:25:41Zen_US
dc.date.available2011-01-05T08:36:14Z
dc.date.created1997en_US
dc.date.issued1997en_US
dc.description.abstractSince the mid-1980s tuberculosis (TB) case numbers and HIV seroprevalence have both risen sharply in sub-Saharan Africa. Estimates for the relative risk of TB in those infected with HIV have ranged from less than five to more than 20. The proportion of TB cases attributable to HIV (the population attributable fraction) has been calculated for several populations but is difficult to interpret if no account is taken of the age and sex distribution of the cases. In a rural area of Malawi we have studied the proportion of TB attributable to HIV over time. Nearly 40 per cent of smear-positive TB cases in this rural area of Malawi can now be attributed directly to HIV. The actual effect of HIV on TB is even greater than this because increased case numbers increase transmission of tuberculosis infection to both HIV-infected and non-infected sections of the population. We compare our findings with others from sub-Saharan Africa and discuss reasons for the differences, and methodological issues in interpretationen_US
dc.format.extent53612 bytesen_US
dc.format.mimetypeapplication/pdfen_US
dc.identifier.urihttp://hdl.handle.net/1885/41321en_US
dc.identifier.urihttp://digitalcollections.anu.edu.au/handle/1885/41321
dc.language.isoen_AUen_US
dc.publisherHealth Transition Centre, National Centre for Epidemiology and Population Health, The Australian National Universityen_US
dc.subjectAfricaen_US
dc.subjectMalawien_US
dc.subjectHIV/AIDSen_US
dc.subjectmorbidityen_US
dc.subjectmortalityen_US
dc.subjecttuberculosisen_US
dc.subjectTBen_US
dc.titleThe impact of HIV on morbidity and mortality from tuberculosis in sub-Saharan Africa: a study of rural Malawi and review of the literatureen_US
dc.typeJournal articleen_US
local.description.refereednoen_US
local.identifier.citationnumbersupp.2en_US
local.identifier.citationpages75-87en_US
local.identifier.citationpublicationHealth Transition Reviewen_US
local.identifier.citationvolume7en_US
local.identifier.citationyear1997en_US
local.identifier.eprintid943en_US
local.rights.ispublishedyesen_US

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