Inhibition of the multidrug resistance P-glycoprotein: time for a change of strategy?
| dc.contributor.author | Luk, F | |
| dc.contributor.author | Bebawy, Mary | |
| dc.contributor.author | Callaghan, Richard | |
| dc.date.accessioned | 2015-12-07T22:38:59Z | |
| dc.date.issued | 2014 | |
| dc.date.updated | 2015-12-07T10:43:40Z | |
| dc.description.abstract | P-glycoprotein (P-gp) is a key player in the multidrug-resistant phenotype in cancer. The protein confers resistance by mediating the ATP-dependent efflux of an astonishing array of anticancer drugs. Its broad specificity has been the subject of numerous | |
| dc.identifier.issn | 0090-9556 | |
| dc.identifier.uri | http://hdl.handle.net/1885/23663 | |
| dc.publisher | American Society for Pharmacology and Experimental Therapeutics | |
| dc.source | Drug Metabolism and Disposition | |
| dc.title | Inhibition of the multidrug resistance P-glycoprotein: time for a change of strategy? | |
| dc.type | Journal article | |
| local.bibliographicCitation.lastpage | 631 | |
| local.bibliographicCitation.startpage | 623 | |
| local.contributor.affiliation | Callaghan, Richard, College of Medicine, Biology and Environment, ANU | |
| local.contributor.affiliation | Luk, F, The University of Technology | |
| local.contributor.affiliation | Bebawy, Mary, The University of Technology | |
| local.contributor.authoruid | Callaghan, Richard, u5103268 | |
| local.description.embargo | 2037-12-31 | |
| local.description.notes | Imported from ARIES | |
| local.identifier.absfor | 060110 - Receptors and Membrane Biology | |
| local.identifier.absfor | 060112 - Structural Biology (incl. Macromolecular Modelling) | |
| local.identifier.absfor | 060199 - Biochemistry and Cell Biology not elsewhere classified | |
| local.identifier.absseo | 970106 - Expanding Knowledge in the Biological Sciences | |
| local.identifier.ariespublication | u4008405xPUB28 | |
| local.identifier.citationvolume | 42 | |
| local.identifier.doi | 10.1124/dmd.113.056176 | |
| local.identifier.scopusID | 2-s2.0-84896131650 | |
| local.identifier.thomsonID | 000332842500017 | |
| local.type.status | Published Version |
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