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Inhibition of the multidrug resistance P-glycoprotein: time for a change of strategy?

dc.contributor.authorLuk, F
dc.contributor.authorBebawy, Mary
dc.contributor.authorCallaghan, Richard
dc.date.accessioned2015-12-07T22:38:59Z
dc.date.issued2014
dc.date.updated2015-12-07T10:43:40Z
dc.description.abstractP-glycoprotein (P-gp) is a key player in the multidrug-resistant phenotype in cancer. The protein confers resistance by mediating the ATP-dependent efflux of an astonishing array of anticancer drugs. Its broad specificity has been the subject of numerous
dc.identifier.issn0090-9556
dc.identifier.urihttp://hdl.handle.net/1885/23663
dc.publisherAmerican Society for Pharmacology and Experimental Therapeutics
dc.sourceDrug Metabolism and Disposition
dc.titleInhibition of the multidrug resistance P-glycoprotein: time for a change of strategy?
dc.typeJournal article
local.bibliographicCitation.lastpage631
local.bibliographicCitation.startpage623
local.contributor.affiliationCallaghan, Richard, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationLuk, F, The University of Technology
local.contributor.affiliationBebawy, Mary, The University of Technology
local.contributor.authoruidCallaghan, Richard, u5103268
local.description.embargo2037-12-31
local.description.notesImported from ARIES
local.identifier.absfor060110 - Receptors and Membrane Biology
local.identifier.absfor060112 - Structural Biology (incl. Macromolecular Modelling)
local.identifier.absfor060199 - Biochemistry and Cell Biology not elsewhere classified
local.identifier.absseo970106 - Expanding Knowledge in the Biological Sciences
local.identifier.ariespublicationu4008405xPUB28
local.identifier.citationvolume42
local.identifier.doi10.1124/dmd.113.056176
local.identifier.scopusID2-s2.0-84896131650
local.identifier.thomsonID000332842500017
local.type.statusPublished Version

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