T Cell determinants incorporating β -amino acid residues are protease resistant and remain immunogenic in vivo

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dc.contributor.authorWebb, Andrew
dc.contributor.authorDunstone, Michelle
dc.contributor.authorWilliamson, Nicholas
dc.contributor.authorPrice, Jason
dc.contributor.authorde Kauwe, Andrea
dc.contributor.authorChen, Weisan
dc.contributor.authorOakley, Aaron
dc.contributor.authorPerlmutter, Patrick
dc.contributor.authorMcCluskey, James
dc.contributor.authorAguilar, Marie-Isabel
dc.contributor.authorRossjohn, J
dc.contributor.authorPurcell, Anthony
dc.date.accessioned2015-12-13T22:53:50Z
dc.date.issued2005
dc.date.updated2015-12-11T11:00:02Z
dc.description.abstractA major hurdle in designing successful epitope-based vaccines resides in the delivery, stability, and immunogenicity of the peptide immunogen. The short-lived nature of unmodified peptide-based vaccines in vivo limits their therapeutic application in the
dc.identifier.issn0022-1767
dc.identifier.urihttp://hdl.handle.net/1885/81986
dc.publisherAmerican Association of Immunologists
dc.sourceJournal of Immunology
dc.source.urihttp://www.jimmunol.org/cgi/content/abstract/175/6/3810
dc.subjectKeywords: antigen; beta amino acid; cross reacting antigen; proteinase; vaccine; amino acid analysis; animal cell; article; cancer immunotherapy; controlled study; drug design; enzyme stability; epitope mapping; immunogenicity; immunoprophylaxis; in vivo study; maj
dc.titleT Cell determinants incorporating β -amino acid residues are protease resistant and remain immunogenic in vivo
dc.typeJournal article
local.bibliographicCitation.issue6
local.bibliographicCitation.lastpage3818
local.bibliographicCitation.startpage3810
local.contributor.affiliationWebb, Andrew, University of Melbourne
local.contributor.affiliationDunstone, Michelle, Monash University
local.contributor.affiliationWilliamson, Nicholas, University of Melbourne
local.contributor.affiliationPrice, Jason, University of Melbourne
local.contributor.affiliationde Kauwe, Andrea, University of Melbourne
local.contributor.affiliationChen, Weisan, Austin Repatriation Medical Centre
local.contributor.affiliationOakley, Aaron, College of Physical and Mathematical Sciences, ANU
local.contributor.affiliationPerlmutter, Patrick, Monash University
local.contributor.affiliationMcCluskey, James, University of Melbourne
local.contributor.affiliationAguilar, Marie-Isabel, Monash University
local.contributor.affiliationRossjohn, J, Monash University
local.contributor.affiliationPurcell, Anthony, University of Melbourne
local.contributor.authoruidOakley, Aaron, u4134401
local.description.embargo2037-12-31
local.description.notesImported from ARIES
local.description.refereedYes
local.identifier.absfor030499 - Medicinal and Biomolecular Chemistry not elsewhere classified
local.identifier.ariespublicationMigratedxPub10289
local.identifier.citationvolume175
local.identifier.scopusID2-s2.0-24744470278
local.type.statusPublished Version

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