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Insights into DNA hydroxymethylation in the honeybee from in-depth analyses of TET dioxygenase

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Wojciechowski, Marek
Rafalski, Dominik
Kucharski, Robert
Misztal, Katarzyna
Maleszka, Joanna
Bochtler, Matthias
Maleszka, Ryszard

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Royal Society Publishing

Abstract

In mammals, a family of TET enzymes producing oxidized forms of 5-methylcytosine (5mC) plays an important role in modulating DNA demethylation dynamics. In contrast, nothing is known about the function of a single TET orthologue present in invertebrates.

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Open Biology

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Open Access

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