Comparative roles of IL-4, IL-13, and IL-4R alpha in dendritic cell maturation and CD4(+) Th2 cell function
Date
2007
Authors
Webb, Dianne
Cai, Yeping
Matthaei, Klaus
Foster, Paul S
Journal Title
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Volume Title
Publisher
American Association of Immunologists
Abstract
IL-4 and IL-13 play key roles in Th2 immunity and asthma pathogenesis. Although the function of these cytokines is partially linked through their shared use of IL-4Rα for signaling, the interplay between these cytokines in the development of memory Th2 r
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Keywords
Keywords: gamma interferon; interleukin 13; interleukin 4; interleukin 4 receptor alpha; adolescent; allergic disease; animal cell; animal experiment; article; asthma; CD4+ T lymphocyte; cell function; cell maturation; coculture; controlled study; cytokine producti
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Source
Journal of Immunology
Type
Journal article
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2037-12-31