Substituent effects in isoxazoles: identification of 4-substituted isoxazoles as Michael acceptors
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Lee, Connie
Easton, Christopher
Gebara-Coghlan, Mariana
Radom, Leo
Scott, Anthony
Simpson, Gregory Wayne
Willis, Anthony
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Royal Society of Chemistry
Abstract
Crystallographic and theoretical studies have been used to investigate substituent effects, which are manifest in electrochemical and yeast-catalysed reactions of 4- and 5-acyl-, alkoxycarbonyl-, cyano- and phenyl-substituted isoxazoles. The results show
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Journal of the Chemical Society, Perkin Transactions 2