Selective modulation of different GABA(A) receptor isoforms by diazepam and etomidate in hippocampal neurons

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Authors

Seymour, Victoria
Curmi, John
Howitt, Susan
Casarotto, Marco
Laver, Derek Rowland
Tierney, Mary (Louise)

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Pergamon-Elsevier Ltd

Abstract

Diazepam modulation of native γ2-containing GABAA (γGABAA) receptors increases channel conductance by facilitating protein interactions involving the γ2-subunit amphipathic (MA) region, which is found in the cytoplasmic loop between transmembrane domai

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The International Journal of Biochemistry and Cell Biology

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Restricted until

2037-12-31