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Chemoselective Ligation Methods Based on the Concept of Native Chemical Ligation

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dc.contributor.authorMalins, L. R.en
dc.contributor.authorPayne, R. J.en
dc.date.accessioned2025-06-11T10:36:02Z
dc.date.available2025-06-11T10:36:02Z
dc.date.issued2021en
dc.description.abstractThis chapter extends from the earlier Science of Synthesis contribution on peptide synthesis (Section 21.11) and focuses on recent developments in chemoselective ligation chemistry based on the logic of native chemical ligation. Synthetic strategies that broaden the scope and versatility of the ligation reaction and that have been widely adopted for the preparation of homogeneous peptides and proteins are highlighted. Methods enabling the efficient preparation of peptide ligation precursors are also included in this chapter.en
dc.description.statusPeer-revieweden
dc.format.extent49en
dc.identifier.isbn9783132442092en
dc.identifier.issn2510-5469en
dc.identifier.scopus85130760020en
dc.identifier.urihttp://www.scopus.com/inward/record.url?scp=85130760020&partnerID=8YFLogxKen
dc.identifier.urihttps://hdl.handle.net/1885/733758541
dc.language.isoenen
dc.publisherGeorg Thieme Verlagen
dc.relation.ispartofKnowledge Updates 2021/3en
dc.relation.ispartofseriesScience of Synthesisen
dc.relation.isversionof3en
dc.rightsPublisher Copyright: © 2021 Georg Thieme Verlag. All rights reserved.en
dc.subjectacyl shiften
dc.subjectamidesen
dc.subjectcysteineen
dc.subjectdeselenizationen
dc.subjectdesulfurizationen
dc.subjectligationen
dc.subjectpeptide couplingen
dc.subjectpeptidesen
dc.subjectproteinsen
dc.subjectselenocysteineen
dc.subjectsolid-phase peptide synthesisen
dc.titleChemoselective Ligation Methods Based on the Concept of Native Chemical Ligationen
dc.typeBook chapteren
dspace.entity.typePublicationen
local.bibliographicCitation.lastpage241en
local.bibliographicCitation.startpage193en
local.contributor.affiliationMalins, L. R.; Chemistry Research, Research School of Chemistry, ANU College of Science and Medicine, The Australian National Universityen
local.identifier.doi10.1055/sos-SD-121-00066en
local.identifier.essn2566-7297en
local.identifier.puree065b531-98ce-4fbb-9736-dad17c896450en
local.identifier.urlhttps://www.scopus.com/pages/publications/85130760020en
local.type.statusPublisheden

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