A publish-subscribe model of genetic networks
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Calcott, Brett; Balcan, Duygu; Hohenlohe, Paul
Description
We present a simple model of genetic regulatory networks in which regulatory connections among genes are mediated by a limited number of signaling molecules. Each gene in our model produces (publishes) a single gene product, which regulates the expression of other genes by binding to regulatory regions that correspond (subscribe) to that product. We explore the consequences of this publish-subscribe model of regulation for the properties of single networks and for the evolution of populations...[Show more]
Collections | ANU Research Publications |
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Date published: | 2008-09-19 |
Type: | Journal article |
URI: | http://hdl.handle.net/10440/469 http://digitalcollections.anu.edu.au/handle/10440/469 |
Source: | PLOS ONE (Public Library of Science) |
DOI: | 10.1371/journal.pone.0003245 |
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Calcott_Publish2008.pdf | 686.95 kB | Adobe PDF |
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